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Deep neural network in HTS sequencing
04-17-2018, 12:28 PM
Post: #1
Deep neural network in HTS sequencing
一款由Google Brain 联合 Alphabet旗下公司Verily所开发的开源工具DeepVariant,巧妙地将HTS序列片段的拼接问题转化为一个图像处理分类问题。DeepVariant利​用了Google Brain的图像处理模型Inception,用深度神经网络来识别HTS测序结果中DNA碱基变异位点,包括基因组上的单碱基突变(SNP)和小的插入缺失(Indel​),从而极大提高了的拼接精度。 
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